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Expression of the Alzheimer protease BACE1 is suppressed via its 5′-untranslated region
The aspartyl protease BACE1 has a pivotal role in the pathogenesis of Alzheimer's disease. Recently, it was shown that in Alzheimer's disease patients, BACE1 levels were elevated although mRNA levels were not changed compared with controls. Here, we demonstrate that the 5′-untranslated reg...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1299076/ https://ncbi.nlm.nih.gov/pubmed/15167888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400166 |
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