Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice

BACKGROUND –: There are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells. We examined the...

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Vydáno v:Biol Psychiatry
Hlavní autoři: Tavares-Ferreira, Diana, Ray, Pradipta R., Sankaranarayanan, Ishwarya, Mejia, Galo L., Wangzhou, Andi, Shiers, Stephanie, Uttarkar, Ruta, Megat, Salim, Barragan-Iglesias, Paulino, Dussor, Gregory, Akopian, Armen N., Price, Theodore J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019688/
https://ncbi.nlm.nih.gov/pubmed/33309016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.09.022
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