Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice

BACKGROUND –: There are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells. We examined the...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Tavares-Ferreira, Diana, Ray, Pradipta R., Sankaranarayanan, Ishwarya, Mejia, Galo L., Wangzhou, Andi, Shiers, Stephanie, Uttarkar, Ruta, Megat, Salim, Barragan-Iglesias, Paulino, Dussor, Gregory, Akopian, Armen N., Price, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019688/
https://ncbi.nlm.nih.gov/pubmed/33309016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.09.022
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