Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice

BACKGROUND –: There are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells. We examined the...

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Publicado en:Biol Psychiatry
Autores principales: Tavares-Ferreira, Diana, Ray, Pradipta R., Sankaranarayanan, Ishwarya, Mejia, Galo L., Wangzhou, Andi, Shiers, Stephanie, Uttarkar, Ruta, Megat, Salim, Barragan-Iglesias, Paulino, Dussor, Gregory, Akopian, Armen N., Price, Theodore J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019688/
https://ncbi.nlm.nih.gov/pubmed/33309016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.09.022
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