Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice

BACKGROUND –: There are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells. We examined the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Psychiatry
Prif Awduron: Tavares-Ferreira, Diana, Ray, Pradipta R., Sankaranarayanan, Ishwarya, Mejia, Galo L., Wangzhou, Andi, Shiers, Stephanie, Uttarkar, Ruta, Megat, Salim, Barragan-Iglesias, Paulino, Dussor, Gregory, Akopian, Armen N., Price, Theodore J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019688/
https://ncbi.nlm.nih.gov/pubmed/33309016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.09.022
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