Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain

Nociceptors, sensory neurons in the DRG that detect damaging or potentially damaging stimuli, are key drivers of neuropathic pain. Injury to these neurons causes activation of translation regulation signaling, including the mechanistic target of rapamycin complex 1 (mTORC1) and mitogen-activated pro...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Megat, Salim, Ray, Pradipta R., Moy, Jamie K., Lou, Tzu-Fang, Barragán-Iglesias, Paulino, Li, Yan, Pradhan, Grishma, Wanghzou, Andi, Ahmad, Ayesha, Burton, Michael D., North, Robert Y., Dougherty, Patrick M., Khoutorsky, Arkady, Sonenberg, Nahum, Webster, Kevin R., Dussor, Gregory, Campbell, Zachary T., Price, Theodore J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2019
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335757/
https://ncbi.nlm.nih.gov/pubmed/30459229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2661-18.2018
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