Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain

Nociceptors, sensory neurons in the DRG that detect damaging or potentially damaging stimuli, are key drivers of neuropathic pain. Injury to these neurons causes activation of translation regulation signaling, including the mechanistic target of rapamycin complex 1 (mTORC1) and mitogen-activated pro...

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發表在:J Neurosci
Main Authors: Megat, Salim, Ray, Pradipta R., Moy, Jamie K., Lou, Tzu-Fang, Barragán-Iglesias, Paulino, Li, Yan, Pradhan, Grishma, Wanghzou, Andi, Ahmad, Ayesha, Burton, Michael D., North, Robert Y., Dougherty, Patrick M., Khoutorsky, Arkady, Sonenberg, Nahum, Webster, Kevin R., Dussor, Gregory, Campbell, Zachary T., Price, Theodore J.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2019
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335757/
https://ncbi.nlm.nih.gov/pubmed/30459229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2661-18.2018
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