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Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice

BACKGROUND –: There are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differences, mostly in immune cells. We examined the...

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Bibliografski detalji
Izdano u:Biol Psychiatry
Glavni autori: Tavares-Ferreira, Diana, Ray, Pradipta R., Sankaranarayanan, Ishwarya, Mejia, Galo L., Wangzhou, Andi, Shiers, Stephanie, Uttarkar, Ruta, Megat, Salim, Barragan-Iglesias, Paulino, Dussor, Gregory, Akopian, Armen N., Price, Theodore J.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019688/
https://ncbi.nlm.nih.gov/pubmed/33309016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.09.022
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