The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer

Targeting mutated oncogenes is an effective approach for treating cancer. The 4 main driver genes of pancreatic ductal adenocarcinoma (PDAC) are KRAS, TP53, CDKN2A, and SMAD4, collectively called the “big 4” of PDAC, however they remain challenging therapeutic targets. In this study, ArfGAP with SH3...

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Bibliografski detalji
Izdano u:Cancer Sci
Glavni autori: Fujii, Atsushi, Masuda, Takaaki, Iwata, Michio, Tobo, Taro, Wakiyama, Hiroaki, Koike, Kensuke, Kosai, Keisuke, Nakano, Takafumi, Kuramitsu, Shotaro, Kitagawa, Akihiro, Sato, Kuniaki, Kouyama, Yuta, Shimizu, Dai, Matsumoto, Yoshihiro, Utsunomiya, Tohru, Ohtsuka, Takao, Yamanishi, Yoshihiro, Nakamura, Masafumi, Mimori, Koshi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
ORIGINAL ARTICLES
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019229/
https://ncbi.nlm.nih.gov/pubmed/33605496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14858
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