The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer

Targeting mutated oncogenes is an effective approach for treating cancer. The 4 main driver genes of pancreatic ductal adenocarcinoma (PDAC) are KRAS, TP53, CDKN2A, and SMAD4, collectively called the “big 4” of PDAC, however they remain challenging therapeutic targets. In this study, ArfGAP with SH3...

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書目詳細資料
發表在:Cancer Sci
Main Authors: Fujii, Atsushi, Masuda, Takaaki, Iwata, Michio, Tobo, Taro, Wakiyama, Hiroaki, Koike, Kensuke, Kosai, Keisuke, Nakano, Takafumi, Kuramitsu, Shotaro, Kitagawa, Akihiro, Sato, Kuniaki, Kouyama, Yuta, Shimizu, Dai, Matsumoto, Yoshihiro, Utsunomiya, Tohru, Ohtsuka, Takao, Yamanishi, Yoshihiro, Nakamura, Masafumi, Mimori, Koshi
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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ORIGINAL ARTICLES
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019229/
https://ncbi.nlm.nih.gov/pubmed/33605496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14858
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