Multiregion Genomic Analysis of Serially Transplanted Patient-derived Xenograft Tumors

Background: Intratumoral heterogeneity (ITH) is a major cause underlying therapeutic difficulty of cancer. Although an understanding of ITH is critically important in order to develop novel therapeutic strategies, experimental models that enable the examination of ITH in a time series are lacking. M...

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Detalles Bibliográficos
Publicado en:Cancer Genomics Proteomics
Main Authors: SATO, KUNIAKI, NIIDA, ATSUSHI, MASUDA, TAKAAKI, SHIMIZU, DAI, TOBO, TARO, KURODA, YOUSUKE, EGUCHI, HIDETOSHI, NAKAGAWA, TAKASHI, SUZUKI, YUTAKA, MIMORI, KOSHI
Formato: Artigo
Idioma:Inglês
Publicado: International Institute of Anticancer Research 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348396/
https://ncbi.nlm.nih.gov/pubmed/30587497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20109
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