Multiregion Genomic Analysis of Serially Transplanted Patient-derived Xenograft Tumors

Background: Intratumoral heterogeneity (ITH) is a major cause underlying therapeutic difficulty of cancer. Although an understanding of ITH is critically important in order to develop novel therapeutic strategies, experimental models that enable the examination of ITH in a time series are lacking. M...

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Pubblicato in:Cancer Genomics Proteomics
Autori principali: SATO, KUNIAKI, NIIDA, ATSUSHI, MASUDA, TAKAAKI, SHIMIZU, DAI, TOBO, TARO, KURODA, YOUSUKE, EGUCHI, HIDETOSHI, NAKAGAWA, TAKASHI, SUZUKI, YUTAKA, MIMORI, KOSHI
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Institute of Anticancer Research 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348396/
https://ncbi.nlm.nih.gov/pubmed/30587497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20109
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