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Multiregion Genomic Analysis of Serially Transplanted Patient-derived Xenograft Tumors

Background: Intratumoral heterogeneity (ITH) is a major cause underlying therapeutic difficulty of cancer. Although an understanding of ITH is critically important in order to develop novel therapeutic strategies, experimental models that enable the examination of ITH in a time series are lacking. M...

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Publicat a:Cancer Genomics Proteomics
Autors principals: SATO, KUNIAKI, NIIDA, ATSUSHI, MASUDA, TAKAAKI, SHIMIZU, DAI, TOBO, TARO, KURODA, YOUSUKE, EGUCHI, HIDETOSHI, NAKAGAWA, TAKASHI, SUZUKI, YUTAKA, MIMORI, KOSHI
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348396/
https://ncbi.nlm.nih.gov/pubmed/30587497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20109
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