Multiregion Genomic Analysis of Serially Transplanted Patient-derived Xenograft Tumors

Background: Intratumoral heterogeneity (ITH) is a major cause underlying therapeutic difficulty of cancer. Although an understanding of ITH is critically important in order to develop novel therapeutic strategies, experimental models that enable the examination of ITH in a time series are lacking. M...

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Gepubliceerd in:Cancer Genomics Proteomics
Hoofdauteurs: SATO, KUNIAKI, NIIDA, ATSUSHI, MASUDA, TAKAAKI, SHIMIZU, DAI, TOBO, TARO, KURODA, YOUSUKE, EGUCHI, HIDETOSHI, NAKAGAWA, TAKASHI, SUZUKI, YUTAKA, MIMORI, KOSHI
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Institute of Anticancer Research 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348396/
https://ncbi.nlm.nih.gov/pubmed/30587497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20109
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