The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer

Targeting mutated oncogenes is an effective approach for treating cancer. The 4 main driver genes of pancreatic ductal adenocarcinoma (PDAC) are KRAS, TP53, CDKN2A, and SMAD4, collectively called the “big 4” of PDAC, however they remain challenging therapeutic targets. In this study, ArfGAP with SH3...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Fujii, Atsushi, Masuda, Takaaki, Iwata, Michio, Tobo, Taro, Wakiyama, Hiroaki, Koike, Kensuke, Kosai, Keisuke, Nakano, Takafumi, Kuramitsu, Shotaro, Kitagawa, Akihiro, Sato, Kuniaki, Kouyama, Yuta, Shimizu, Dai, Matsumoto, Yoshihiro, Utsunomiya, Tohru, Ohtsuka, Takao, Yamanishi, Yoshihiro, Nakamura, Masafumi, Mimori, Koshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019229/
https://ncbi.nlm.nih.gov/pubmed/33605496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14858
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