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The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer

Targeting mutated oncogenes is an effective approach for treating cancer. The 4 main driver genes of pancreatic ductal adenocarcinoma (PDAC) are KRAS, TP53, CDKN2A, and SMAD4, collectively called the “big 4” of PDAC, however they remain challenging therapeutic targets. In this study, ArfGAP with SH3...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Fujii, Atsushi, Masuda, Takaaki, Iwata, Michio, Tobo, Taro, Wakiyama, Hiroaki, Koike, Kensuke, Kosai, Keisuke, Nakano, Takafumi, Kuramitsu, Shotaro, Kitagawa, Akihiro, Sato, Kuniaki, Kouyama, Yuta, Shimizu, Dai, Matsumoto, Yoshihiro, Utsunomiya, Tohru, Ohtsuka, Takao, Yamanishi, Yoshihiro, Nakamura, Masafumi, Mimori, Koshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019229/
https://ncbi.nlm.nih.gov/pubmed/33605496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14858
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