Histone deacetylase 3 promotes innate antiviral immunity through deacetylation of TBK1

TANK-binding kinase 1 (TBK1), a core kinase of antiviral pathways, activates the production of interferons (IFNs). It has been reported that deacetylation activates TBK1; however, the precise mechanism still remains to be uncovered. We show here that during the early stage of viral infection, the ac...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Tang, Jie-lin, Yang, Qi, Xu, Chong-hui, Zhao, He, Liu, Ya-ling, Liu, Can-yu, Zhou, Yuan, Gai, Dong-wei, Pei, Rong-juan, Wang, Yun, Hu, Xue, Zhong, Bo, Wang, Yan-yi, Chen, Xin-wen, Chen, Ji-zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018997/
https://ncbi.nlm.nih.gov/pubmed/32772249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00751-5
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