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Complement C3a induces axonal hypomyelination in the periventricular white matter through activation of WNT/β‐catenin signal pathway in septic neonatal rats experimentally induced by lipopolysaccharide

Neuroinflammation is thought to play a pivotal role in the pathogenesis of periventricular white matter (PWM) damage (PWMD) induced by neonatal sepsis. Because the complement cascade is implicated in inflammatory response, this study was carried out to determine whether C3a is involved in PWMD, and,...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Huang, Peixian, Zhou, Qiuping, Lin, Qiongyu, Lin, Lanfen, Wang, Huifang, Chen, Xuan, Jiang, Shuqi, Fu, Hui, Deng, Yiyu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018074/
https://ncbi.nlm.nih.gov/pubmed/31622511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12798
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