Complement C3a induces axonal hypomyelination in the periventricular white matter through activation of WNT/β‐catenin signal pathway in septic neonatal rats experimentally induced by lipopolysaccharide

Neuroinflammation is thought to play a pivotal role in the pathogenesis of periventricular white matter (PWM) damage (PWMD) induced by neonatal sepsis. Because the complement cascade is implicated in inflammatory response, this study was carried out to determine whether C3a is involved in PWMD, and,...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Huang, Peixian, Zhou, Qiuping, Lin, Qiongyu, Lin, Lanfen, Wang, Huifang, Chen, Xuan, Jiang, Shuqi, Fu, Hui, Deng, Yiyu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018074/
https://ncbi.nlm.nih.gov/pubmed/31622511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12798
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