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Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia
Red cells from patients with sickle cell anaemia (SCA) contain the abnormal haemoglobin HbS. Under hypoxic conditions, HbS polymerises and causes red cell sickling, a rise in intracellular Ca(2+) and exposure of phosphatidylserine (PS). These changes make sickle cells sticky and liable to lodge in t...
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| 出版年: | Front Physiol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017214/ https://ncbi.nlm.nih.gov/pubmed/33815154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.653545 |
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