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Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia
Red cells from patients with sickle cell anaemia (SCA) contain the abnormal haemoglobin HbS. Under hypoxic conditions, HbS polymerises and causes red cell sickling, a rise in intracellular Ca(2+) and exposure of phosphatidylserine (PS). These changes make sickle cells sticky and liable to lodge in t...
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| Publié dans: | Front Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017214/ https://ncbi.nlm.nih.gov/pubmed/33815154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.653545 |
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