The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study

INTRODUCTION: Therapeutic acetaminophen (APAP) ingestion causes asymptomatic drug–induced liver injury in some patients. In most cases, elevations in alanine aminotransferase (ALT) are transient and return to the normal range, even with continued APAP ingestion, though ALT elevation persists in some...

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Détails bibliographiques
Publié dans:J Med Toxicol
Auteurs principaux: Monte, Andrew A., Sonn, Brandon, Saben, Jessica, Rumack, Barry H., Reynolds, Kate M., Dart, Richard C., Heard, Kennon J.
Format: Artigo
Langue:Inglês
Publié: Springer US 2020
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017040/
https://ncbi.nlm.nih.gov/pubmed/33051802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-020-00815-2
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