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Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing

BACKGROUND: Paracetamol protein adducts (PPA) are a biomarker of paracetamol exposure. PPA are quantified as paracetamol–cysteine (APAP‐CYS), and concentrations above 1.1 μmol l(–1) have been suggested as a marker of paracetamol‐induced hepatotoxicity. However, there is little information on the ran...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Clin Pharmacol
Päätekijät: Heard, Kennon, Green, Jody L., Anderson, Victoria, Bucher‐Bartelson, Becki, Dart, Richard C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767203/
https://ncbi.nlm.nih.gov/pubmed/26584404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12831
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