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Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing
BACKGROUND: Paracetamol protein adducts (PPA) are a biomarker of paracetamol exposure. PPA are quantified as paracetamol–cysteine (APAP‐CYS), and concentrations above 1.1 μmol l(–1) have been suggested as a marker of paracetamol‐induced hepatotoxicity. However, there is little information on the ran...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767203/ https://ncbi.nlm.nih.gov/pubmed/26584404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12831 |
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