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Acetaminophen-cysteine adducts during therapeutic dosing and following overdose

BACKGROUND: Acetaminophen-cysteine adducts (APAP-CYS) are a specific biomarker of acetaminophen exposure. APAP-CYS concentrations have been described in the setting of acute overdose, and a concentration >1.1 nmol/ml has been suggested as a marker of hepatic injury from acetaminophen overdose in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heard, Kennon J, Green, Jody L, James, Laura P, Judge, Bryan S, Zolot, Liza, Rhyee, Sean, Dart, Richard C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066114/
https://ncbi.nlm.nih.gov/pubmed/21401949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-20
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