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The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study

INTRODUCTION: Therapeutic acetaminophen (APAP) ingestion causes asymptomatic drug–induced liver injury in some patients. In most cases, elevations in alanine aminotransferase (ALT) are transient and return to the normal range, even with continued APAP ingestion, though ALT elevation persists in some...

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Detalhes bibliográficos
Publicado no:J Med Toxicol
Main Authors: Monte, Andrew A., Sonn, Brandon, Saben, Jessica, Rumack, Barry H., Reynolds, Kate M., Dart, Richard C., Heard, Kennon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017040/
https://ncbi.nlm.nih.gov/pubmed/33051802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-020-00815-2
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