The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study

INTRODUCTION: Therapeutic acetaminophen (APAP) ingestion causes asymptomatic drug–induced liver injury in some patients. In most cases, elevations in alanine aminotransferase (ALT) are transient and return to the normal range, even with continued APAP ingestion, though ALT elevation persists in some...

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Опубликовано в: :J Med Toxicol
Главные авторы: Monte, Andrew A., Sonn, Brandon, Saben, Jessica, Rumack, Barry H., Reynolds, Kate M., Dart, Richard C., Heard, Kennon J.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017040/
https://ncbi.nlm.nih.gov/pubmed/33051802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-020-00815-2
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