DNA-driven condensation assembles the meiotic DNA break machinery

Accurate segregation of chromosomes during meiosis—critical for genome stability across sexual cycles—relies on homologous recombination initiated by DNA double-strand breaks (DSBs) made by the Spo11 protein(1,2). DSB formation is regulated and tied to the elaboration of large-scale chromosome struc...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Bouuaert, Corentin Claeys, Pu, Stephen, Wang, Juncheng, Oger, Cédric, Daccache, Dima, Xie, Wei, Patel, Dinshaw J., Keeney, Scott
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016751/
https://ncbi.nlm.nih.gov/pubmed/33731927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03374-w
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