Identification of a Potent and Selective 5-HT(1A) Receptor Agonist with In Vitro and In Vivo Antinociceptive Activity

[Image: see text] Opioids are the gold standard drugs for the treatment of acute and chronic severe pain, although their serious side effects constitute a big limitation. In the search for new and safer drugs, 5-HT(1A)R agonists are emerging as potential candidates in pain relief therapy. In this wo...

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Vydáno v:ACS Chem Neurosci
Hlavní autoři: Linciano, Pasquale, Sorbi, Claudia, Comitato, Antonella, Lesniak, Anna, Bujalska-Zadrożny, Magdalena, Pawłowska, Agata, Bielenica, Anna, Orzelska-Górka, Jolanta, Kędzierska, Ewa, Biała, Grażyna, Ronsisvalle, Simone, Limoncella, Silvia, Casarini, Livio, Cichero, Elena, Fossa, Paola, Satała, Grzegorz, Bojarski, Andrzej J., Brasili, Livio, Bardoni, Rita, Franchini, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016166/
https://ncbi.nlm.nih.gov/pubmed/33263393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00289
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