Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy

The propagation of conformational strains by templated seeding is central to the prion concept. Seeded assembly of α‐synuclein into filaments is believed to underlie the prion‐like spreading of protein inclusions in a number of human neurodegenerative diseases, including Parkinson's disease, de...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Lövestam, Sofia, Schweighauser, Manuel, Matsubara, Tomoyasu, Murayama, Shigeo, Tomita, Taisuke, Ando, Takashi, Hasegawa, Kazuko, Yoshida, Mari, Tarutani, Airi, Hasegawa, Masato, Goedert, Michel, Scheres, Sjors H. W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016116/
https://ncbi.nlm.nih.gov/pubmed/33548114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13110
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados