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A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells
Transcriptional enhancers are critical for development and phenotype evolution and are often mutated in disease contexts; however, even in well-studied cell types, the sequence code conferring enhancer activity remains unknown. To examine the enhancer regulatory code for pluripotent stem cells, we i...
Uloženo v:
| Vydáno v: | Genome Res |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8015845/ https://ncbi.nlm.nih.gov/pubmed/33712417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.272468.120 |
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