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The Role of Somatic Mutations in Acute Myeloid Leukemia Pathogenesis

Acute myeloid leukemia (AML) is characterized by attenuation of lineage differentiation trajectories that results in impaired hematopoiesis and enhanced self-renewal. To date, sequencing studies have provided a rich landscape of information on the somatic mutations that contribute to AML pathogenesi...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Kishtagari, Ashwin, Levine, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015698/
https://ncbi.nlm.nih.gov/pubmed/32398288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a034975
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