Telomere Length and Associations with Somatic Mutations and Clinical Outcomes in Acute Myeloid Leukemia

We examined the genetic implications and clinical impact of telomere length (TL) in 67 patients with acute myeloid leukemia (AML). There was a trend toward improved survival at 6 months in patients with longer TL. We found that patients with activating mutations, such as FLT3-ITD, had shorter TL, wh...

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Detalhes bibliográficos
Publicado no:Leuk Res
Main Authors: Watts, Justin M., Dumitriu, Bogdan, Hilden, Patrick, Kishtagari, Ashwin, Rapaport, Franck, Chen, Christina, Ahn, Jihae, Devlin, Sean M., Stein, Eytan M., Rampal, Raajit, Levine, Ross L., Young, Neal, Tallman, Martin S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526052/
https://ncbi.nlm.nih.gov/pubmed/27568819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.07.013
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