Telomere Length and Associations with Somatic Mutations and Clinical Outcomes in Acute Myeloid Leukemia

We examined the genetic implications and clinical impact of telomere length (TL) in 67 patients with acute myeloid leukemia (AML). There was a trend toward improved survival at 6 months in patients with longer TL. We found that patients with activating mutations, such as FLT3-ITD, had shorter TL, wh...

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Bibliografiset tiedot
Julkaisussa:Leuk Res
Päätekijät: Watts, Justin M., Dumitriu, Bogdan, Hilden, Patrick, Kishtagari, Ashwin, Rapaport, Franck, Chen, Christina, Ahn, Jihae, Devlin, Sean M., Stein, Eytan M., Rampal, Raajit, Levine, Ross L., Young, Neal, Tallman, Martin S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526052/
https://ncbi.nlm.nih.gov/pubmed/27568819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.07.013
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