Telomere Length and Associations with Somatic Mutations and Clinical Outcomes in Acute Myeloid Leukemia

We examined the genetic implications and clinical impact of telomere length (TL) in 67 patients with acute myeloid leukemia (AML). There was a trend toward improved survival at 6 months in patients with longer TL. We found that patients with activating mutations, such as FLT3-ITD, had shorter TL, wh...

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Udgivet i:Leuk Res
Main Authors: Watts, Justin M., Dumitriu, Bogdan, Hilden, Patrick, Kishtagari, Ashwin, Rapaport, Franck, Chen, Christina, Ahn, Jihae, Devlin, Sean M., Stein, Eytan M., Rampal, Raajit, Levine, Ross L., Young, Neal, Tallman, Martin S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526052/
https://ncbi.nlm.nih.gov/pubmed/27568819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.07.013
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