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Biological and clinical implications of telomere dysfunction in myeloid malignancies
Telomeres at the ends of linear chromosomes protect the genome. Telomeres shorten with each round of cell division, placing a finite limit on cell growth. Telomere attrition is associated with cell senescence and apoptosis. Telomerase, a specialized ribonucleoprotein complex, maintains telomeres hom...
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| Publicado no: | Ther Adv Hematol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652659/ https://ncbi.nlm.nih.gov/pubmed/29093807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620717731549 |
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