Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Somatic mutations of the CUT-like homeobox 1 (CUX1) gene (CUX1(MT)) can be found in myeloid neoplasms (MNs), in particular, in myelodysplastic syndromes (MDSs). The CUX1 locus is also deleted in 3 of 4 MN cases with −7/del(7q). A cohort of 1480 MN patients was used to characterize clinical features...

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發表在:Blood Adv
Main Authors: Aly, Mai, Ramdzan, Zubaidah M., Nagata, Yasunobu, Balasubramanian, Suresh K., Hosono, Naoko, Makishima, Hideki, Visconte, Valeria, Kuzmanovic, Teodora, Adema, Vera, Nazha, Aziz, Przychodzen, Bartlomiej P., Kerr, Cassandra M., Sekeres, Mikkael A., Abazeed, Mohamed E., Nepveu, Alain, Maciejewski, Jaroslaw P.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2019
主題:
Myeloid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650742/
https://ncbi.nlm.nih.gov/pubmed/31320321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028423
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