Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Somatic mutations of the CUT-like homeobox 1 (CUX1) gene (CUX1(MT)) can be found in myeloid neoplasms (MNs), in particular, in myelodysplastic syndromes (MDSs). The CUX1 locus is also deleted in 3 of 4 MN cases with −7/del(7q). A cohort of 1480 MN patients was used to characterize clinical features...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Aly, Mai, Ramdzan, Zubaidah M., Nagata, Yasunobu, Balasubramanian, Suresh K., Hosono, Naoko, Makishima, Hideki, Visconte, Valeria, Kuzmanovic, Teodora, Adema, Vera, Nazha, Aziz, Przychodzen, Bartlomiej P., Kerr, Cassandra M., Sekeres, Mikkael A., Abazeed, Mohamed E., Nepveu, Alain, Maciejewski, Jaroslaw P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2019
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650742/
https://ncbi.nlm.nih.gov/pubmed/31320321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028423
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