Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Somatic mutations of the CUT-like homeobox 1 (CUX1) gene (CUX1(MT)) can be found in myeloid neoplasms (MNs), in particular, in myelodysplastic syndromes (MDSs). The CUX1 locus is also deleted in 3 of 4 MN cases with −7/del(7q). A cohort of 1480 MN patients was used to characterize clinical features...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Aly, Mai, Ramdzan, Zubaidah M., Nagata, Yasunobu, Balasubramanian, Suresh K., Hosono, Naoko, Makishima, Hideki, Visconte, Valeria, Kuzmanovic, Teodora, Adema, Vera, Nazha, Aziz, Przychodzen, Bartlomiej P., Kerr, Cassandra M., Sekeres, Mikkael A., Abazeed, Mohamed E., Nepveu, Alain, Maciejewski, Jaroslaw P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650742/
https://ncbi.nlm.nih.gov/pubmed/31320321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028423
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