Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Somatic mutations of the CUT-like homeobox 1 (CUX1) gene (CUX1(MT)) can be found in myeloid neoplasms (MNs), in particular, in myelodysplastic syndromes (MDSs). The CUX1 locus is also deleted in 3 of 4 MN cases with −7/del(7q). A cohort of 1480 MN patients was used to characterize clinical features...

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Publicat a:Blood Adv
Autors principals: Aly, Mai, Ramdzan, Zubaidah M., Nagata, Yasunobu, Balasubramanian, Suresh K., Hosono, Naoko, Makishima, Hideki, Visconte, Valeria, Kuzmanovic, Teodora, Adema, Vera, Nazha, Aziz, Przychodzen, Bartlomiej P., Kerr, Cassandra M., Sekeres, Mikkael A., Abazeed, Mohamed E., Nepveu, Alain, Maciejewski, Jaroslaw P.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650742/
https://ncbi.nlm.nih.gov/pubmed/31320321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028423
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