Acute myeloid leukemia ontogeny is defined by distinct somatic mutations

Acute myeloid leukemia (AML) can develop after an antecedent myeloid malignancy (secondary AML [s-AML]), after leukemogenic therapy (therapy-related AML [t-AML]), or without an identifiable prodrome or known exposure (de novo AML). The genetic basis of these distinct pathways of AML development has...

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Veröffentlicht in:Blood
Hauptverfasser: Lindsley, R. Coleman, Mar, Brenton G., Mazzola, Emanuele, Grauman, Peter V., Shareef, Sarah, Allen, Steven L., Pigneux, Arnaud, Wetzler, Meir, Stuart, Robert K., Erba, Harry P., Damon, Lloyd E., Powell, Bayard L., Lindeman, Neal, Steensma, David P., Wadleigh, Martha, DeAngelo, Daniel J., Neuberg, Donna, Stone, Richard M., Ebert, Benjamin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Plenary Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342352/
https://ncbi.nlm.nih.gov/pubmed/25550361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-610543
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