The histone modification H3K4me3 is altered at the ANK1 locus in Alzheimer's disease brain

Several epigenome-wide association studies of DNA methylation have highlighted altered DNA methylation in the ANK1 gene in Alzheimer's disease (AD) brain samples. However, no study has specifically examined ANK1 histone modifications in the disease. We use chromatin immunoprecipitation-qPCR to...

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Detalhes bibliográficos
Publicado no:Future Sci OA
Main Authors: Smith, Adam R, Smith, Rebecca G, Macdonald, Ruby, Marzi, Sarah J, Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Mill, Jonathan, Lunnon, Katie
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2021
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015672/
https://ncbi.nlm.nih.gov/pubmed/33815817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/fsoa-2020-0161
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