Variation in 5-hydroxymethylcytosine across human cortex and cerebellum

BACKGROUND: The most widely utilized approaches for quantifying DNA methylation involve the treatment of genomic DNA with sodium bisulfite; however, this method cannot distinguish between 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC). Previous studies have shown that 5hmC is enriched in...

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Gepubliceerd in:Genome Biol
Hoofdauteurs: Lunnon, Katie, Hannon, Eilis, Smith, Rebecca G., Dempster, Emma, Wong, Chloe, Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Kepa, Agnieszka, Schalkwyk, Leonard, Mill, Jonathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756397/
https://ncbi.nlm.nih.gov/pubmed/26883014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0871-x
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