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Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight

IGF2 is a paternally expressed imprinted gene with an important role in development and brain function. Allele-specific expression of IGF2 is regulated by DNA methylation at three differentially methylated regions (DMRs) spanning the IGF2/H19 domain on human 11p15.5. We have comprehensively assessed...

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Bibliografiset tiedot
Päätekijät: Pidsley, Ruth, Dempster, Emma, Troakes, Claire, Al-Sarraj, Safa, Mill, Jonathan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335909/
https://ncbi.nlm.nih.gov/pubmed/22395465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.2.18910
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