DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice

BACKGROUND: Insulin-like growth factor 2 (Igf2) is a paternally expressed imprinted gene regulating fetal growth, playing an integral role in the development of many tissues including the brain. The parent-of-origin specific expression of Igf2 is largely controlled by allele-specific DNA methylation...

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Main Authors: Pidsley, Ruth, Fernandes, Cathy, Viana, Joana, Paya-Cano, Jose L, Liu, Lin, Smith, Rebecca G, Schalkwyk, Leonard C, Mill, Jonathan
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541153/
https://ncbi.nlm.nih.gov/pubmed/23216893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-42
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