The histone modification H3K4me3 is altered at the ANK1 locus in Alzheimer's disease brain

Several epigenome-wide association studies of DNA methylation have highlighted altered DNA methylation in the ANK1 gene in Alzheimer's disease (AD) brain samples. However, no study has specifically examined ANK1 histone modifications in the disease. We use chromatin immunoprecipitation-qPCR to...

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Vydáno v:Future Sci OA
Hlavní autoři: Smith, Adam R, Smith, Rebecca G, Macdonald, Ruby, Marzi, Sarah J, Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Mill, Jonathan, Lunnon, Katie
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Science Ltd 2021
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015672/
https://ncbi.nlm.nih.gov/pubmed/33815817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/fsoa-2020-0161
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