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HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression

BACKGROUND: Hepatoma is a common malignancy of the liver. The abnormal high expression of alpha-fetoprotein (AFP) is intimately associated with hepatoma progress, but the mechanism of transcriptional regulation and singularly activation of AFP gene in hepatoma is not clear. METHODS: The expression o...

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Pubblicato in:J Exp Clin Cancer Res
Autori principali: Cao, Zhengyi, Cheng, Yuning, Wang, Jiyin, Liu, Yujuan, Yang, Ruixiang, Jiang, Wei, Li, Hui, Zhang, Xiaowei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015059/
https://ncbi.nlm.nih.gov/pubmed/33794968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01881-2
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