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A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis

Oxidative stress can induce cell dysfunction and lead to a broad range of degenerative alterations, including carcinogenesis, aging, and other oxidative stress-related conditions. To avoid undergoing carcinogenesis in response to oxidative stress, cells trigger a succession of checkpoint responses,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Shuya, Cao, Zhengyi, Xue, Junhui, Li, Hui, Jiang, Wei, Cheng, Yuning, Li, Gang, Zhang, Xiaowei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437229/
https://ncbi.nlm.nih.gov/pubmed/28348080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.768101
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