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The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence

Oncogene-mediated premature senescence has emerged as a potential tumor-suppressive mechanism in early cancer transitions. Previous work shows that RAS and p38 MAPK participate in premature senescence, but transcriptional effectors have not been identified. Here, we demonstrate that the HBP1 transcr...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaowei, Kim, Jiyoung, Ruthazer, Robin, McDevitt, Michael A., Wazer, David E., Paulson, K. Eric, Yee, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636767/
https://ncbi.nlm.nih.gov/pubmed/16966377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00604-06
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