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Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1
In certain cancers, constitutive Wnt signaling results from mutation in one or more pathway components. The result is the accumulation and nuclear localization of β-catenin, which interacts with the lymphoid enhancer factor-1 (LEF)/T-cell factor (TCF) family of HMG-box transcription factors, which a...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2001
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125566/ https://ncbi.nlm.nih.gov/pubmed/11500377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.16.4500 |
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