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All Tcf HMG box transcription factors interact with Groucho-related co-repressors

Tcf/Lef family transcription factors are the downstream effectors of the Wingless/Wnt signal transduction pathway. Upon Wingless/Wnt signalling, β-catenin translocates to the nucleus, interacts with Tcf (1–3) and thus activates transcription of target genes (4,5). Tcf factors also interact with memb...

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Detalhes bibliográficos
Main Authors: Brantjes, Helen, Roose, Jeroen, van de Wetering, Marc, Clevers, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31284/
https://ncbi.nlm.nih.gov/pubmed/11266540
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