Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1

In certain cancers, constitutive Wnt signaling results from mutation in one or more pathway components. The result is the accumulation and nuclear localization of β-catenin, which interacts with the lymphoid enhancer factor-1 (LEF)/T-cell factor (TCF) family of HMG-box transcription factors, which a...

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Bibliographic Details

Published in:	EMBO J
Main Authors:	Sampson, Ellen M., Haque, Zaffar K., Ku, Man-Ching, Tevosian, Sergei G., Albanese, Chris, Pestell, Richard G., Paulson, K.Eric, Yee, Amy S.
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2001
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4500
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