Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1

In certain cancers, constitutive Wnt signaling results from mutation in one or more pathway components. The result is the accumulation and nuclear localization of β-catenin, which interacts with the lymphoid enhancer factor-1 (LEF)/T-cell factor (TCF) family of HMG-box transcription factors, which a...

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Pubblicato in:	EMBO J
Autori principali:	Sampson, Ellen M., Haque, Zaffar K., Ku, Man-Ching, Tevosian, Sergei G., Albanese, Chris, Pestell, Richard G., Paulson, K.Eric, Yee, Amy S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4500
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