Sequestration and Inhibition of Daxx-Mediated Transcriptional Repression by PML

PML fuses with retinoic acid receptor α (RARα) in the t(15;17) translocation that causes acute promyelocytic leukemia (APL). In addition to localizing diffusely throughout the nucleoplasm, PML mainly resides in discrete nuclear structures known as PML oncogenic domains (PODs), which are disrupted in...

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Autores principales: Li, Hui, Leo, Christopher, Zhu, Jiang, Wu, Xiaoyang, O'Neil, Jennifer, Park, Eun-Ju, Chen, J. Don
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC85360/
https://ncbi.nlm.nih.gov/pubmed/10669754
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