Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics

Pro-inflammatory signaling mediated by Toll-like receptor 4 (TLR4)/myeloid differentiation-2 (MD-2) complex plays a crucial role in the instantaneous protection against infectious challenge and largely contributes to recovery from Gram-negative infection. Activation of TLR4 also boosts the adaptive...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Heine, Holger, Adanitsch, Florian, Peternelj, Tina Tinkara, Haegman, Mira, Kasper, Christoph, Ittig, Simon, Beyaert, Rudi, Jerala, Roman, Zamyatina, Alla
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012497/
https://ncbi.nlm.nih.gov/pubmed/33815382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.631797
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