UDP-glucose and P2Y(14) receptor amplify allergen-induced airway eosinophilia

Airway eosinophilia is a hallmark of allergic asthma and is associated with mucus production, airway hyperresponsiveness, and shortness of breath. Although glucocorticoids are widely used to treat asthma, their prolonged use is associated with several side effects. Furthermore, many individuals with...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Karcz, Tadeusz P., Whitehead, Gregory S., Nakano, Keiko, Nakano, Hideki, Grimm, Sara A., Williams, Jason G., Deterding, Leesa J., Jacobson, Kenneth A., Cook, Donald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011887/
https://ncbi.nlm.nih.gov/pubmed/33792561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140709
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