Direct coupling of oligomerization and oligomerization-driven endocytosis of the dopamine transporter to its conformational mechanics and activity

Dopamine transporter (DAT) mediates the reuptake of synaptically released dopamine, and thus controls the duration and intensity of dopamine neurotransmission. Mammalian DAT has been observed to form oligomers, although the mechanisms of oligomerization and its role in DAT activity and trafficking r...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Sorkina, Tatiana, Cheng, Mary Hongying, Bagalkot, Tarique R., Wallace, Callen, Watkins, Simon C., Bahar, Ivet, Sorkin, Alexander
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010718/
https://ncbi.nlm.nih.gov/pubmed/33610553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100430
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars