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(3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) regulation of hypothalamic and extrahypothalamic corticotropin releasing factor (CRF): Sexual dimorphism and brain region specificity in Sprague Dawley rats

CRF is the main activator of the hypothalamic-pituitary-adrenal (HPA) axis in response to stress. CRF neurons are found mainly in the hypothalamus, but CRF positive cells and CRF1 receptors are also found in extrahypothalamic structures, including amygdala (CeA), hippocampus, NAc and VTA. CRF releas...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Boero, Giorgia, Tyler, Ryan E., Todd, Caroline A., O’Buckley, Todd K., Balan, Irina, Besheer, Joyce, Morrow, A. Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010646/
https://ncbi.nlm.nih.gov/pubmed/33460689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2021.108463
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