Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis

BACKGROUND: Significantly elevated serum and hepatic bile acid (BA) concentrations have been known to occur in patients with liver fibrosis. However, the roles of different BA species in liver fibrogenesis are not fully understood. METHODS: We quantitatively measured blood BA concentrations in nonal...

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Gepubliceerd in:EBioMedicine
Hoofdauteurs: Xie, Guoxiang, Jiang, Runqiu, Wang, Xiaoning, Liu, Ping, Zhao, Aihua, Wu, Yiran, Huang, Fengjie, Liu, Zhipeng, Rajani, Cynthia, Zheng, Xiaojiao, Qiu, Jiannan, Zhang, Xiaoling, Zhao, Suwen, Bian, Hua, Gao, Xin, Sun, Beicheng, Jia, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010625/
https://ncbi.nlm.nih.gov/pubmed/33752128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103290
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