Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis

BACKGROUND: Significantly elevated serum and hepatic bile acid (BA) concentrations have been known to occur in patients with liver fibrosis. However, the roles of different BA species in liver fibrogenesis are not fully understood. METHODS: We quantitatively measured blood BA concentrations in nonal...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Xie, Guoxiang, Jiang, Runqiu, Wang, Xiaoning, Liu, Ping, Zhao, Aihua, Wu, Yiran, Huang, Fengjie, Liu, Zhipeng, Rajani, Cynthia, Zheng, Xiaojiao, Qiu, Jiannan, Zhang, Xiaoling, Zhao, Suwen, Bian, Hua, Gao, Xin, Sun, Beicheng, Jia, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010625/
https://ncbi.nlm.nih.gov/pubmed/33752128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103290
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