Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis

BACKGROUND: Significantly elevated serum and hepatic bile acid (BA) concentrations have been known to occur in patients with liver fibrosis. However, the roles of different BA species in liver fibrogenesis are not fully understood. METHODS: We quantitatively measured blood BA concentrations in nonal...

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Foilsithe in:EBioMedicine
Main Authors: Xie, Guoxiang, Jiang, Runqiu, Wang, Xiaoning, Liu, Ping, Zhao, Aihua, Wu, Yiran, Huang, Fengjie, Liu, Zhipeng, Rajani, Cynthia, Zheng, Xiaojiao, Qiu, Jiannan, Zhang, Xiaoling, Zhao, Suwen, Bian, Hua, Gao, Xin, Sun, Beicheng, Jia, Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2021
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010625/
https://ncbi.nlm.nih.gov/pubmed/33752128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103290
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