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CYP3A5 genotype affects time to therapeutic tacrolimus level in pediatric kidney transplant recipients
BACKGROUND: Optimal management of immunosuppression in kidney transplantation requires a delicate balance of efficacy and toxicity. Tacrolimus (TAC) dose requirements are significantly impacted by genetic variation in CYP3A5 polymorphisms, however the impact that genotype has on clinical outcomes in...
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| Publicado no: | Pediatr Transplant |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009482/ https://ncbi.nlm.nih.gov/pubmed/31124575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/petr.13494 |
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